Investigation of Enantiomer Elution Order of Selected Chiral Sulphoxides in High-Performance Liquid Chromatography with Polysaccharide-Based Chiral Columns and Polar Organic Mobile Phases

Author: Maia Gegenava
Co-authors: Maia Gegenava, Bezhan Chankvetadze
Keywords: Chiral sulphoxides, Separation of enantiomers
Annotation:

Investigation of Enantiomer Elution Order of Selected Chiral Sulphoxides in High-Performance Liquid Chromatography with Polysaccharide-Based Chiral Columns and Polar Organic Mobile Phases Maia Gegenava, Bezhan Chankvetadze In the present work the enantiomer elution order of chiral sulphoxides has been studied in HPLC by using polar-organic mobile phases and novel type of chiral columns such as Lux Cellulose-1, Lux Cellulose-2, Lux Cellulose-3, Lux Cellulose-4, Lux Amylose-2 and SP-6. The interesting examples of the enantiomer elution order reversal were found based on the composition of the stationary, as well the mobile phase.